STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4837 aa)    
Predicted Functional Partners:
PIAS4
Protein inhibitor of activated STAT 4.
   
 0.920
NEURL4
Neuralized E3 ubiquitin protein ligase 4.
   
 
 0.878
MAPK6
Mitogen-activated protein kinase 6.
    
 0.839
USP32
Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family.
   
 
 0.745
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
0.729
TRIM36
Tripartite motif containing 36.
      
 0.705
UBR4
Ubiquitin protein ligase E3 component n-recognin 4.
   
 
 0.686
RMND5A
Required for meiotic nuclear division 5 homolog A.
      
 0.666
LRIF1
Ligand dependent nuclear receptor interacting factor 1.
   
  
 0.661
DOCK10
Dedicator of cytokinesis 10; Belongs to the DOCK family.
   
  0.657
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.