STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM4ALysine demethylase 4A. (1065 aa)    
Predicted Functional Partners:
KDM1A
Lysine demethylase 1A.
   
 0.941
KDM3A
Lysine demethylase 3A.
     
 0.839
KDM3B
Lysine demethylase 3B.
   
 
 0.793
KDM2B
Lysine demethylase 2B.
   
 
 0.710
KDM6B
Lysine demethylase 6B.
   
 
 0.702
KDM4B
Lysine demethylase 4B.
  
 
0.638
KDM6A
Lysine demethylase 6A.
   
 
 0.613
NSD2
Nuclear receptor binding SET domain protein 2.
   
 
 0.611
TP53BP1
Tumor protein p53 binding protein 1.
   
 
 0.566
LOC102148494
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.564
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.