STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YTHDC1YTH domain containing 1. (781 aa)    
Predicted Functional Partners:
METTL14
Methyltransferase like 14; Belongs to the MT-A70-like family.
   
 
 0.922
ALKBH5
AlkB homolog 5, RNA demethylase.
      
 0.871
WTAP
WT1 associated protein.
   
 
 0.859
HNRNPC
RRM domain-containing protein.
   
 
 0.857
ZC3H13
Zinc finger CCCH-type containing 13.
   
  
 0.848
LOC100053336
Serine/arginine-rich splicing factor 3.
   
 
 0.834
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
    
 
 0.833
SRSF3
Splicing factor, arginine/serine-rich 3-like protein.
   
 
 0.833
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 
 0.829
CSTF1
Cleavage stimulation factor subunit 1.
    
 
 0.824
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.