STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNASE2Deoxyribonuclease 2, lysosomal. (353 aa)    
Predicted Functional Partners:
DNASE2B
Deoxyribonuclease 2 beta.
  
  
0.912
SPATA48
Spermatogenesis associated 48.
      
 0.908
JPT2
Jupiter microtubule associated homolog 2.
      
 0.742
RNASEH2C
Ribonuclease H2 subunit C.
      
 0.731
SKIV2L
Ski2 like RNA helicase.
      
 0.707
THSD7A
Thrombospondin type 1 domain containing 7A.
   
  
 0.697
TMPRSS9
Transmembrane serine protease 9; Belongs to the peptidase S1 family.
   
  
 0.692
FIGNL1
Fidgetin like 1; Belongs to the AAA ATPase family.
   
 
 0.686
RNPEPL1
Arginyl aminopeptidase like 1.
      
 0.635
DNASE1
Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (By similarity). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation. Degradation of intra [...]
      
 0.602
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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