ZNF653 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZNF653

Zinc finger protein 653. (627 aa)

Predicted Functional Partners:

RNF166

0.847

CRBN

0.746

RAB28

0.717

NAE1

0.714

LMBRD2

0.521

UBA3

0.516

ESCO2

0.493

GMFB

0.481

WIZ

0.471

ZNF827

0.470

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRBN	NAE1	ENSECAP00000045867	ENSECAP00000038752	Cereblon.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.656
CRBN	RNF166	ENSECAP00000045867	ENSECAP00000010692	Cereblon.	Ring finger protein 166.	0.488
CRBN	ZNF653	ENSECAP00000045867	ENSECAP00000016829	Cereblon.	Zinc finger protein 653.	0.746
CRBN	ZNF827	ENSECAP00000045867	ENSECAP00000019125	Cereblon.	Zinc finger protein 827.	0.681
ESCO2	ZNF653	ENSECAP00000010711	ENSECAP00000016829	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Zinc finger protein 653.	0.493
GMFB	LMBRD2	ENSECAP00000022936	ENSECAP00000017510	Cornichon family AMPA receptor auxiliary protein 1.	LMBR1 domain containing 2.	0.493
GMFB	ZNF653	ENSECAP00000022936	ENSECAP00000016829	Cornichon family AMPA receptor auxiliary protein 1.	Zinc finger protein 653.	0.481
LMBRD2	GMFB	ENSECAP00000017510	ENSECAP00000022936	LMBR1 domain containing 2.	Cornichon family AMPA receptor auxiliary protein 1.	0.493
LMBRD2	ZNF653	ENSECAP00000017510	ENSECAP00000016829	LMBR1 domain containing 2.	Zinc finger protein 653.	0.521
NAE1	CRBN	ENSECAP00000038752	ENSECAP00000045867	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Cereblon.	0.656
NAE1	RAB28	ENSECAP00000038752	ENSECAP00000011699	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	RAB28, member RAS oncogene family.	0.486
NAE1	RNF166	ENSECAP00000038752	ENSECAP00000010692	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ring finger protein 166.	0.580
NAE1	UBA3	ENSECAP00000038752	ENSECAP00000043479	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin like modifier activating enzyme 3.	0.999
NAE1	ZNF653	ENSECAP00000038752	ENSECAP00000016829	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Zinc finger protein 653.	0.714
NAE1	ZNF827	ENSECAP00000038752	ENSECAP00000019125	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Zinc finger protein 827.	0.589
RAB28	NAE1	ENSECAP00000011699	ENSECAP00000038752	RAB28, member RAS oncogene family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.486
RAB28	RNF166	ENSECAP00000011699	ENSECAP00000010692	RAB28, member RAS oncogene family.	Ring finger protein 166.	0.566
RAB28	UBA3	ENSECAP00000011699	ENSECAP00000043479	RAB28, member RAS oncogene family.	Ubiquitin like modifier activating enzyme 3.	0.450
RAB28	WIZ	ENSECAP00000011699	ENSECAP00000027637	RAB28, member RAS oncogene family.	Uncharacterized protein.	0.559
RAB28	ZNF653	ENSECAP00000011699	ENSECAP00000016829	RAB28, member RAS oncogene family.	Zinc finger protein 653.	0.717