STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL8A1Collagen type VIII alpha 1 chain. (735 aa)    
Predicted Functional Partners:
COL8A2
Collagen type VIII alpha 2 chain.
  
0.933
COL21A1
Collagen type XXI alpha 1 chain.
  
0.691
REN
Renin; Belongs to the peptidase A1 family.
      
 0.638
COL6A2
Collagen type VI alpha 2 chain.
  
0.637
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
   
 0.628
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
 0.623
P3H3
Prolyl 3-hydroxylase 3.
   
 0.615
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
   
 0.615
P3H2
Prolyl 3-hydroxylase 2.
   
 0.603
COL1A2
Collagen type I alpha 2 chain.
  
0.593
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.