STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEGF8Multiple EGF like domains 8. (2789 aa)    
Predicted Functional Partners:
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.936
DCLK3
Doublecortin like kinase 3.
      
 0.799
MGRN1
Mahogunin ring finger 1.
   
 
 0.769
RBM23
RNA binding motif protein 23.
      
 0.740
THOC6
THO complex 6.
      
 0.738
RNF157
Ring finger protein 157.
   
 
 0.718
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor.
      
 0.699
PTPRN
Protein tyrosine phosphatase receptor type N.
    
 
 0.671
CARD19
Caspase recruitment domain family member 19.
      
 0.661
IFRD1
Interferon related developmental regulator 1.
      
 0.648
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.