STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD2T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. (347 aa)    
Predicted Functional Partners:
CD58
CD58 molecule.
   
 0.996
CD3E
CD3e molecule.
   
 
 0.946
CD5
CD5 molecule.
   
 
 0.894
CD4
CD4 molecule.
   
 0.888
CD28
CD28 molecule.
   
  
 0.870
CD2AP
CD2 associated protein.
   
 
 0.849
CD8A
CD8a molecule.
   
  
 0.832
CD3D
CD3d molecule.
   
 0.829
CD247
CD247 molecule.
   
 
 0.811
CD6
CD6 molecule.
   
 0.796
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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