STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL22Interleukin-22-like protein. (189 aa)    
Predicted Functional Partners:
IL22RA1
Interleukin 22 receptor subunit alpha 1.
    
 0.999
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.983
IL22RA2
Interleukin 22 receptor subunit alpha 2.
    
 0.981
IL23R
Interleukin 23 receptor.
     
 0.960
IL17A
Uncharacterized protein.
   
  
 0.953
IL26
Interleukin 26.
   
  
 0.931
IL17F
Interleukin 17F.
   
  
 0.922
STAT3
Signal transducer and activator of transcription.
     
 0.889
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.886
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
  
 0.877
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]