STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNA1Cyclin A1; Belongs to the cyclin family. (456 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.999
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.999
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.998
E2F1
E2F transcription factor 1.
   
 0.996
SKP2
S-phase kinase associated protein 2.
   
 0.991
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.989
RB1
RB transcriptional corepressor 1.
   
 0.986
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
0.984
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.983
CDKN1C
Cyclin dependent kinase inhibitor 1C.
    
 0.983
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.