STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGASCyclic GMP-AMP synthase. (581 aa)    
Predicted Functional Partners:
IRF3
Interferon regulatory factor 3.
      
 0.896
TBK1
TANK binding kinase 1.
      
 0.821
AIM2
Absent in melanoma 2.
   
 
 0.808
DDX41
DEAD-box helicase 41.
      
 0.800
MAVS
Mitochondrial antiviral signaling protein.
      
 0.775
IFNB1
Interferon beta; Has antiviral, antibacterial and anticancer activities.
      
 0.769
STING1
Transmembrane protein 173.
    
 0.754
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
  
 0.689
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
   
  
 0.684
IRF7
Interferon regulatory factor 7.
   
  
 0.675
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.