STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF13BTumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (290 aa)    
Predicted Functional Partners:
TNFRSF13C
B cell-activating factor receptor.
    
 0.998
TNFRSF17
TNF receptor superfamily member 17.
    
 0.995
TNFRSF13B
TNF receptor superfamily member 13B.
    
 0.985
TNFSF12
Uncharacterized protein; Belongs to the tumor necrosis factor family.
   
 
0.813
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 
 0.740
TNFSF11
Tumor necrosis factor ligand superfamily member.
   
 0.693
LTB
Tumor necrosis factor ligand 1C; Belongs to the tumor necrosis factor family.
   
 
 0.681
TNF
Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]
   
 
 0.672
TNFSF14
Tumor necrosis factor ligand 1D.
   
 
 0.659
LTBR
Lymphotoxin beta receptor.
   
 0.659
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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