STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF4TNF receptor superfamily member 4. (320 aa)    
Predicted Functional Partners:
TNFSF4
Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family.
    
 0.998
TNFRSF18
TNF receptor superfamily member 18.
   
  
 0.854
KLRG2
Killer cell lectin like receptor G2.
   
  
 0.777
TNFRSF8
TNF receptor superfamily member 8.
   
  
 0.761
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
      
 0.690
HAVCR2
Hepatitis A virus cellular receptor 2.
    
 
 0.684
FCGRT
Fc fragment of IgG receptor and transporter; Belongs to the MHC class I family.
      
 0.668
CD70
Tumor necrosis factor ligand 8A; Belongs to the tumor necrosis factor family.
   
  
 0.644
TNFSF9
TNF superfamily member 9; Belongs to the tumor necrosis factor family.
   
  
 0.642
HHLA2
HERV-H LTR-associating 2.
   
  
 0.639
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.