STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLAAPhospholipase A2 activating protein. (863 aa)    
Predicted Functional Partners:
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
   
 
 0.966
FAAP100
FA core complex associated protein 100.
   
 
 0.860
NPLOC4
NPL4 homolog, ubiquitin recognition factor.
   
 
 0.860
NSFL1C
NSFL1 cofactor.
   
 
 0.857
UBXN2B
UBX domain protein 2B.
   
 
 0.842
UBC
Ubiquitin B.
    
 0.826
UBC-2
Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...]
    
 0.826
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.801
UBXN7
UBX domain protein 7.
   
 
 0.773
UBXN1
UBX domain protein 1.
    
 
 0.750
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.