node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF4 | ATF6 | ENSECAP00000004969 | ENSECAP00000043374 | Activating transcription factor 4. | Activating transcription factor 6. | 0.934 |
ATF4 | ATF6B | ENSECAP00000004969 | ENSECAP00000019270 | Activating transcription factor 4. | Activating transcription factor 6 beta. | 0.933 |
ATF4 | DDIT3 | ENSECAP00000004969 | ENSECAP00000017986 | Activating transcription factor 4. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.996 |
ATF4 | NFE2L2 | ENSECAP00000004969 | ENSECAP00000051248 | Activating transcription factor 4. | Nuclear factor, erythroid 2 like 2. | 0.546 |
ATF4 | XBP1 | ENSECAP00000004969 | ENSECAP00000050875 | Activating transcription factor 4. | BZIP domain-containing protein. | 0.934 |
ATF6 | ATF4 | ENSECAP00000043374 | ENSECAP00000004969 | Activating transcription factor 6. | Activating transcription factor 4. | 0.934 |
ATF6 | ATF6B | ENSECAP00000043374 | ENSECAP00000019270 | Activating transcription factor 6. | Activating transcription factor 6 beta. | 0.917 |
ATF6 | DDIT3 | ENSECAP00000043374 | ENSECAP00000017986 | Activating transcription factor 6. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.994 |
ATF6 | XBP1 | ENSECAP00000043374 | ENSECAP00000050875 | Activating transcription factor 6. | BZIP domain-containing protein. | 0.984 |
ATF6B | ATF4 | ENSECAP00000019270 | ENSECAP00000004969 | Activating transcription factor 6 beta. | Activating transcription factor 4. | 0.933 |
ATF6B | ATF6 | ENSECAP00000019270 | ENSECAP00000043374 | Activating transcription factor 6 beta. | Activating transcription factor 6. | 0.917 |
ATF6B | DDIT3 | ENSECAP00000019270 | ENSECAP00000017986 | Activating transcription factor 6 beta. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.937 |
ATF6B | XBP1 | ENSECAP00000019270 | ENSECAP00000050875 | Activating transcription factor 6 beta. | BZIP domain-containing protein. | 0.648 |
BCL2L11 | DDIT3 | ENSECAP00000051866 | ENSECAP00000017986 | BCL2 like 11. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.941 |
DDIT3 | ATF4 | ENSECAP00000017986 | ENSECAP00000004969 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Activating transcription factor 4. | 0.996 |
DDIT3 | ATF6 | ENSECAP00000017986 | ENSECAP00000043374 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Activating transcription factor 6. | 0.994 |
DDIT3 | ATF6B | ENSECAP00000017986 | ENSECAP00000019270 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Activating transcription factor 6 beta. | 0.937 |
DDIT3 | BCL2L11 | ENSECAP00000017986 | ENSECAP00000051866 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | BCL2 like 11. | 0.941 |
DDIT3 | MAPK11 | ENSECAP00000017986 | ENSECAP00000004442 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Mitogen-activated protein kinase. | 0.932 |
DDIT3 | MAPK12 | ENSECAP00000017986 | ENSECAP00000015310 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Mitogen-activated protein kinase. | 0.928 |