STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.999
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.994
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.982
CCNA1
Cyclin A1; Belongs to the cyclin family.
  
0.981
CDKN1C
Cyclin dependent kinase inhibitor 1C.
   
 0.981
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.980
RB1
RB transcriptional corepressor 1.
   
 0.978
SKP2
S-phase kinase associated protein 2.
   
 0.977
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.977
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.976
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.