STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA3Protein disulfide-isomerase. (505 aa)    
Predicted Functional Partners:
CALR
Calreticulin.
   
 0.999
TAPBP
TAP binding protein.
   
 0.999
CANX
Calnexin.
   
 0.996
LOC100062428
Calreticulin.
   
 0.994
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.986
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
   
 0.985
TAP2
Uncharacterized protein.
   
 0.967
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
0.865
HYOU1
Hypoxia up-regulated 1.
   
 0.843
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
 0.830
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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