node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDO | GOT1 | ENSECAP00000005482 | ENSECAP00000000135 | D-aspartate oxidase. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.926 |
DDO | GOT1L1 | ENSECAP00000005482 | ENSECAP00000013482 | D-aspartate oxidase. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.984 |
DDO | GOT2 | ENSECAP00000005482 | ENSECAP00000014550 | D-aspartate oxidase. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.920 |
DDO | IDH1 | ENSECAP00000005482 | ENSECAP00000010194 | D-aspartate oxidase. | Isocitrate dehydrogenase (NADP(+)) 1, cytosolic. | 0.871 |
DDO | IL4I1 | ENSECAP00000005482 | ENSECAP00000015625 | D-aspartate oxidase. | Interleukin 4 induced 1. | 0.905 |
DDO | LOC100055246 | ENSECAP00000005482 | ENSECAP00000017508 | D-aspartate oxidase. | Amine oxidase. | 0.918 |
DDO | LOC100147151 | ENSECAP00000005482 | ENSECAP00000012687 | D-aspartate oxidase. | Amine oxidase. | 0.913 |
DDO | NIT2 | ENSECAP00000005482 | ENSECAP00000018562 | D-aspartate oxidase. | Nitrilase family member 2. | 0.918 |
DDO | OGDH | ENSECAP00000005482 | ENSECAP00000021678 | D-aspartate oxidase. | Oxoglutarate dehydrogenase. | 0.823 |
GLUD1 | GOT1 | ENSECAP00000044983 | ENSECAP00000000135 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.962 |
GLUD1 | GOT1L1 | ENSECAP00000044983 | ENSECAP00000013482 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.952 |
GLUD1 | GOT2 | ENSECAP00000044983 | ENSECAP00000014550 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.962 |
GLUD1 | IDH1 | ENSECAP00000044983 | ENSECAP00000010194 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Isocitrate dehydrogenase (NADP(+)) 1, cytosolic. | 0.975 |
GLUD1 | NIT2 | ENSECAP00000044983 | ENSECAP00000018562 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Nitrilase family member 2. | 0.945 |
GLUD1 | OGDH | ENSECAP00000044983 | ENSECAP00000021678 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Oxoglutarate dehydrogenase. | 0.889 |
GOT1 | DDO | ENSECAP00000000135 | ENSECAP00000005482 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | D-aspartate oxidase. | 0.926 |
GOT1 | GLUD1 | ENSECAP00000000135 | ENSECAP00000044983 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.962 |
GOT1 | GOT1L1 | ENSECAP00000000135 | ENSECAP00000013482 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Glutamic-oxaloacetic transaminase 1 like 1. | 0.913 |
GOT1 | GOT2 | ENSECAP00000000135 | ENSECAP00000014550 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.982 |
GOT1 | IDH1 | ENSECAP00000000135 | ENSECAP00000010194 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | Isocitrate dehydrogenase (NADP(+)) 1, cytosolic. | 0.896 |