STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (662 aa)    
Predicted Functional Partners:
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
    
 
 0.953
MIP
Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.833
FTCD
Formimidoyltransferase cyclodeaminase.
   
  
 0.712
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
  
 0.622
CRYBB3
Crystallin beta B3; Belongs to the beta/gamma-crystallin family.
  
  
 0.591
CRYGS
Crystallin gamma S; Belongs to the beta/gamma-crystallin family.
   
  
 0.573
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
   
  
 0.570
RAB9B
RAB9B, member RAS oncogene family.
      
 0.562
SYNM
Synemin; Belongs to the intermediate filament family.
    
 
 0.542
TMOD4
Tropomodulin 4.
      
 0.526
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.