STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB14Growth factor receptor bound protein 14. (540 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.914
IGF1R
Tyrosine-protein kinase receptor.
    
 0.817
SREBF1
Sterol regulatory element binding transcription factor 1.
      
 0.718
PERP
P53 apoptosis effector related to PMP22.
      
 0.664
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.657
TEK
TEK receptor tyrosine kinase.
   
 0.631
FRS3
Fibroblast growth factor receptor substrate 3.
   
 0.594
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1.
      
 0.584
FRMD4B
FERM domain containing 4B.
   
 
 0.580
FGFR2
Fibroblast growth factor receptor.
   
 0.574
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.