PUM1 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PUM1

Pumilio RNA binding family member 1. (1223 aa)

Predicted Functional Partners:

ATXN1

0.911

ATXN1L

0.903

NANOS1

0.866

CLINT1

0.837

CNOT7

0.821

PLSCR1

0.711

NANOS2

0.700

SH3D19

0.693

GAK

0.688

ENSECAP00000036580

0.672

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN1	ATXN1L	ENSECAP00000048555	ENSECAP00000038150	Ataxin 1.	Ataxin 1 like.	0.922
ATXN1	PUM1	ENSECAP00000048555	ENSECAP00000018948	Ataxin 1.	Pumilio RNA binding family member 1.	0.911
ATXN1L	ATXN1	ENSECAP00000038150	ENSECAP00000048555	Ataxin 1 like.	Ataxin 1.	0.922
ATXN1L	PUM1	ENSECAP00000038150	ENSECAP00000018948	Ataxin 1 like.	Pumilio RNA binding family member 1.	0.903
CLINT1	GAK	ENSECAP00000033688	ENSECAP00000021630	Clathrin interactor 1.	Cyclin G associated kinase.	0.923
CLINT1	PUM1	ENSECAP00000033688	ENSECAP00000018948	Clathrin interactor 1.	Pumilio RNA binding family member 1.	0.837
CLINT1	SH3D19	ENSECAP00000033688	ENSECAP00000050443	Clathrin interactor 1.	SH3 domain containing 19.	0.730
CNOT7	NANOS2	ENSECAP00000004072	ENSECAP00000004189	CCR4-NOT transcription complex subunit 7.	Nanos C2HC-type zinc finger 2; Belongs to the nanos family.	0.732
CNOT7	PUM1	ENSECAP00000004072	ENSECAP00000018948	CCR4-NOT transcription complex subunit 7.	Pumilio RNA binding family member 1.	0.821
ENSECAP00000036580	PLSCR1	ENSECAP00000036580	ENSECAP00000015132	Uncharacterized protein.	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.	0.481
ENSECAP00000036580	PUM1	ENSECAP00000036580	ENSECAP00000018948	Uncharacterized protein.	Pumilio RNA binding family member 1.	0.672
GAK	CLINT1	ENSECAP00000021630	ENSECAP00000033688	Cyclin G associated kinase.	Clathrin interactor 1.	0.923
GAK	PUM1	ENSECAP00000021630	ENSECAP00000018948	Cyclin G associated kinase.	Pumilio RNA binding family member 1.	0.688
GAK	SH3D19	ENSECAP00000021630	ENSECAP00000050443	Cyclin G associated kinase.	SH3 domain containing 19.	0.407
NANOS1	PUM1	ENSECAP00000002470	ENSECAP00000018948	Nanos C2HC-type zinc finger 1; Belongs to the nanos family.	Pumilio RNA binding family member 1.	0.866
NANOS2	CNOT7	ENSECAP00000004189	ENSECAP00000004072	Nanos C2HC-type zinc finger 2; Belongs to the nanos family.	CCR4-NOT transcription complex subunit 7.	0.732
NANOS2	PUM1	ENSECAP00000004189	ENSECAP00000018948	Nanos C2HC-type zinc finger 2; Belongs to the nanos family.	Pumilio RNA binding family member 1.	0.700
PLSCR1	ENSECAP00000036580	ENSECAP00000015132	ENSECAP00000036580	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.	Uncharacterized protein.	0.481
PLSCR1	PUM1	ENSECAP00000015132	ENSECAP00000018948	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.	Pumilio RNA binding family member 1.	0.711
PUM1	ATXN1	ENSECAP00000018948	ENSECAP00000048555	Pumilio RNA binding family member 1.	Ataxin 1.	0.911