STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM7SF2Transmembrane 7 superfamily member 2. (415 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.987
DHCR24
24-dehydrocholesterol reductase.
 
 
 0.980
MSMO1
C-4 methylsterol oxidase-like protein; Belongs to the sterol desaturase family.
   
 0.973
EBP
3-beta-hydroxysteroid-Delta(8) Delta(7)-isomerase-like protein.
   
 
 0.948
SC5D
Lathosterol oxidase-like protein; Belongs to the sterol desaturase family.
   
 0.942
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.925
SQLE
Squalene epoxidase.
   
 
 0.924
LBR
Lamin B receptor.
  
  
 
0.902
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating-like protein; Belongs to the 3-beta-HSD family.
   
 
 0.877
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.803
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.