STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (900 aa)    
Predicted Functional Partners:
CTNNB1
Beta catenin 1.
   
 0.999
CTNND1
Catenin delta 1.
   
 0.985
JUP
Junction plakoglobin.
   
 0.985
CTNNA1
Catenin alpha 1.
   
 0.977
CTNNA2
Catenin alpha 2.
    
 0.977
CTNNA3
Catenin alpha 3.
    
 0.965
MMP9
Matrix metallopeptidase 9.
    
 0.956
ADAM10
ADAM metallopeptidase domain 10.
     
 0.916
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.
   
 0.893
CASP3
Caspase-3-like protein; Belongs to the peptidase C14A family.
   
 0.891
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.