STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYRFMyelin regulatory factor. (1186 aa)    
Predicted Functional Partners:
OLIG2
Oligodendrocyte transcription factor 2.
      
 0.867
PLP1
Proteolipid protein 1.
      
 0.851
MBP
Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
      
 0.824
ENPP6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
      
 0.778
SOX10
SRY-box transcription factor 10.
   
  
 0.778
RFFL
Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.
      
 0.770
OLIG1
Oligodendrocyte transcription factor 1.
      
 0.734
PPP1R32
Protein phosphatase 1 regulatory subunit 32.
      
 0.703
GPR17
G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.654
MAG
Myelin associated glycoprotein.
   
  
 0.619
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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