STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL3Kelch like family member 3. (601 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.988
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.925
WNK4
WNK lysine deficient protein kinase 4.
    
 
 0.916
MON1A
MON1 homolog A, secretory trafficking associated.
      
 0.740
CDHR4
Cadherin related family member 4.
      
 0.736
RBX1
Ring-box 1.
    
 0.733
RNF123
Ring finger protein 123.
    
 0.724
WNK3
WNK lysine deficient protein kinase 3.
   
 
 0.675
KEAP1
Kelch like ECH associated protein 1.
  
 
 
0.671
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.651
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.