STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A11Solute carrier family 25 member 11; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)    
Predicted Functional Partners:
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
 
 0.843
ATAD3A
ATPase family AAA domain containing 3A.
   
 
 0.768
MDH2
Malate dehydrogenase.
   
  
 0.756
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
   
  
 0.683
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8.
   
  
 0.675
TUFM
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.666
GOT2
Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).
   
  
 0.641
VDAC2
Voltage dependent anion channel 2.
   
 
 0.624
AIFM1
Apoptosis inducing factor mitochondria associated 1.
    
 
 0.602
NDUFV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
   
  
 0.596
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.