STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMDT1Single-pass membrane protein with aspartate rich tail 1. (107 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.998
MCU
Mitochondrial calcium uniporter.
    
 0.997
MICU2
Mitochondrial calcium uptake 2.
   
 0.990
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.989
MICU3
Mitochondrial calcium uptake family member 3.
     
 0.983
NDUFA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
  
 0.836
ATP5MF
ATP synthase membrane subunit f.
   
  
 0.788
NDUFB11
NADH:ubiquinone oxidoreductase subunit B11.
   
  
 0.718
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.684
EDF1
Endothelial differentiation related factor 1.
   
    0.669
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.