STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PWP1PWP1 homolog, endonuclein. (500 aa)    
Predicted Functional Partners:
RPF2
Brix domain-containing protein 1-like protein.
   
 
 0.950
CXCL9
Multifunctional fusion protein; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.
   
  
 0.937
GRWD1
Glutamate rich WD repeat containing 1.
   
  
0.925
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
   
 
 0.923
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.921
BRIX1
Biogenesis of ribosomes BRX1.
   
 
 0.919
EBNA1BP2
rRNA-processing protein EBP2-like protein.
   
 
 0.918
WDR3
WD repeat domain 3.
   
  
 0.917
TSR1
TSR1 ribosome maturation factor.
   
  
 0.905
PWP2
Uncharacterized protein.
   
  
 0.905
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.