STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCE1Phosphoinositide phospholipase C. (2299 aa)    
Predicted Functional Partners:
HRAS
HRas proto-oncogene, GTPase.
    
 0.996
NRAS
NRAS proto-oncogene, GTPase.
    
 0.996
KRAS
KRAS proto-oncogene, GTPase.
    
 0.949
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.945
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 
 0.929
RRAS
RAS related.
   
 0.918
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
   
 
 0.917
RAP1B
Ras-related protein Rap-1b-like protein.
    
 0.916
LOC100049912
Uncharacterized protein.
    
 0.916
MRAS
Muscle RAS oncogene homolog.
   
  0.916
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.