STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRHRThyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (398 aa)    
Predicted Functional Partners:
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
     
 0.997
LOC100050529
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
  
  
 
0.902
GNA14
G protein subunit alpha 14.
    
 0.790
GNAQ
G protein subunit alpha q.
    
 0.787
GNA11
G protein subunit alpha 11.
    
 0.787
GNA15
G protein subunit alpha 15.
    
  0.782
TSHB
Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism.
   
 
 0.721
OR51T1
Olfactory receptor.
      
 0.651
GNRHR
Gonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G- proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family.
   
 
 0.635
KCNV1
Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family.
      
 0.634
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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