MTRR protein (Equus caballus) - STRING interaction network

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Score

MTRR

5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (786 aa)

Predicted Functional Partners:

MTR

0.981

BHMT2

0.847

MTHFR

0.836

BHMT

0.772

MMADHC

0.762

FLAD1

0.754

MMACHC

0.753

LOC100146156

0.745

LOC100057612

0.745

ENOPH1

0.737

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BHMT	BHMT2	ENSECAP00000013444	ENSECAP00000016031	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	0.903
BHMT	ENOPH1	ENSECAP00000013444	ENSECAP00000017163	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.739
BHMT	LOC100057612	ENSECAP00000013444	ENSECAP00000020500	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.937
BHMT	LOC100146156	ENSECAP00000013444	ENSECAP00000019510	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.937
BHMT	MMADHC	ENSECAP00000013444	ENSECAP00000031473	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Metabolism of cobalamin associated D.	0.536
BHMT	MTHFR	ENSECAP00000013444	ENSECAP00000038098	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.939
BHMT	MTR	ENSECAP00000013444	ENSECAP00000019784	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.942
BHMT	MTRR	ENSECAP00000013444	ENSECAP00000020761	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.772
BHMT2	BHMT	ENSECAP00000016031	ENSECAP00000013444	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	0.903
BHMT2	ENOPH1	ENSECAP00000016031	ENSECAP00000017163	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.825
BHMT2	LOC100057612	ENSECAP00000016031	ENSECAP00000020500	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.937
BHMT2	LOC100146156	ENSECAP00000016031	ENSECAP00000019510	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.937
BHMT2	MMADHC	ENSECAP00000016031	ENSECAP00000031473	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Metabolism of cobalamin associated D.	0.536
BHMT2	MTHFR	ENSECAP00000016031	ENSECAP00000038098	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.971
BHMT2	MTR	ENSECAP00000016031	ENSECAP00000019784	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.940
BHMT2	MTRR	ENSECAP00000016031	ENSECAP00000020761	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.847
ENOPH1	BHMT	ENSECAP00000017163	ENSECAP00000013444	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	0.739
ENOPH1	BHMT2	ENSECAP00000017163	ENSECAP00000016031	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	0.825
ENOPH1	MTHFR	ENSECAP00000017163	ENSECAP00000038098	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.640
ENOPH1	MTR	ENSECAP00000017163	ENSECAP00000019784	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.641