STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF41Zinc finger protein 41. (769 aa)    
Predicted Functional Partners:
TBXA2R
Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.792
PTGDR
Prostaglandin D2 receptor.
      
 0.720
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 0.666
PTGER3
Prostaglandin E receptor 3.
      
 0.651
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
      
 0.634
MED17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.600
C2
Complement C2; Belongs to the peptidase S1 family.
    
 
 0.566
GPR65
Psychosine receptor-like protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.561
PHTF2
Putative homeodomain transcription factor 2.
    
 0.527
RDH11
Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.523
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.