F3 protein (Equus caballus) - STRING interaction network

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Score

F3

Coagulation factor III, tissue factor. (388 aa)

Predicted Functional Partners:

F7

0.988

TFPI

0.906

TFPI2

0.887

THBD

0.862

VWF

0.816

PLAT

0.755

SELP

0.722

PLG

0.719

F2

0.703

SERPINE1

0.678

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F2	F3	ENSECAP00000009701	ENSECAP00000020955	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor III, tissue factor.	0.703
F2	F7	ENSECAP00000009701	ENSECAP00000004108	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VII.	0.768
F2	PLAT	ENSECAP00000009701	ENSECAP00000046326	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator, tissue type.	0.447
F2	PLG	ENSECAP00000009701	ENSECAP00000034982	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasmin heavy chain A; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be m [...]	0.912
F2	SELP	ENSECAP00000009701	ENSECAP00000009403	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Selectin P.	0.441
F2	SERPINE1	ENSECAP00000009701	ENSECAP00000017450	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family E member 1; Belongs to the serpin family.	0.551
F2	TFPI	ENSECAP00000009701	ENSECAP00000050197	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Tissue factor pathway inhibitor.	0.708
F2	TFPI2	ENSECAP00000009701	ENSECAP00000016920	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Tissue factor pathway inhibitor.	0.493
F2	THBD	ENSECAP00000009701	ENSECAP00000003584	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Thrombomodulin.	0.998
F2	VWF	ENSECAP00000009701	ENSECAP00000029404	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Von Willebrand factor.	0.925
F3	F2	ENSECAP00000020955	ENSECAP00000009701	Coagulation factor III, tissue factor.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.703
F3	F7	ENSECAP00000020955	ENSECAP00000004108	Coagulation factor III, tissue factor.	Coagulation factor VII.	0.988
F3	PLAT	ENSECAP00000020955	ENSECAP00000046326	Coagulation factor III, tissue factor.	Plasminogen activator, tissue type.	0.755
F3	PLG	ENSECAP00000020955	ENSECAP00000034982	Coagulation factor III, tissue factor.	Plasmin heavy chain A; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be m [...]	0.719
F3	SELP	ENSECAP00000020955	ENSECAP00000009403	Coagulation factor III, tissue factor.	Selectin P.	0.722
F3	SERPINE1	ENSECAP00000020955	ENSECAP00000017450	Coagulation factor III, tissue factor.	Serpin family E member 1; Belongs to the serpin family.	0.678
F3	TFPI	ENSECAP00000020955	ENSECAP00000050197	Coagulation factor III, tissue factor.	Tissue factor pathway inhibitor.	0.906
F3	TFPI2	ENSECAP00000020955	ENSECAP00000016920	Coagulation factor III, tissue factor.	Tissue factor pathway inhibitor.	0.887
F3	THBD	ENSECAP00000020955	ENSECAP00000003584	Coagulation factor III, tissue factor.	Thrombomodulin.	0.862
F3	VWF	ENSECAP00000020955	ENSECAP00000029404	Coagulation factor III, tissue factor.	Von Willebrand factor.	0.816