node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CARD9 | PRKCD | ENSECAP00000016941 | ENSECAP00000021032 | Caspase recruitment domain family member 9. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.988 |
CARD9 | PRKCE | ENSECAP00000016941 | ENSECAP00000002661 | Caspase recruitment domain family member 9. | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] | 0.433 |
NCF1 | NCF2 | ENSECAP00000012958 | ENSECAP00000006755 | Neutrophil cytosolic factor 1. | Neutrophil cytosolic factor 2. | 0.999 |
NCF1 | NCF4 | ENSECAP00000012958 | ENSECAP00000036740 | Neutrophil cytosolic factor 1. | Neutrophil cytosolic factor 4. | 0.999 |
NCF1 | PRKCA | ENSECAP00000012958 | ENSECAP00000036198 | Neutrophil cytosolic factor 1. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.960 |
NCF1 | PRKCB | ENSECAP00000012958 | ENSECAP00000042034 | Neutrophil cytosolic factor 1. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.950 |
NCF1 | PRKCD | ENSECAP00000012958 | ENSECAP00000021032 | Neutrophil cytosolic factor 1. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.946 |
NCF1 | RAC2 | ENSECAP00000012958 | ENSECAP00000036738 | Neutrophil cytosolic factor 1. | Rac family small GTPase 2. | 0.994 |
NCF2 | NCF1 | ENSECAP00000006755 | ENSECAP00000012958 | Neutrophil cytosolic factor 2. | Neutrophil cytosolic factor 1. | 0.999 |
NCF2 | NCF4 | ENSECAP00000006755 | ENSECAP00000036740 | Neutrophil cytosolic factor 2. | Neutrophil cytosolic factor 4. | 0.999 |
NCF2 | PRKCB | ENSECAP00000006755 | ENSECAP00000042034 | Neutrophil cytosolic factor 2. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.924 |
NCF2 | PRKCD | ENSECAP00000006755 | ENSECAP00000021032 | Neutrophil cytosolic factor 2. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.945 |
NCF2 | RAC2 | ENSECAP00000006755 | ENSECAP00000036738 | Neutrophil cytosolic factor 2. | Rac family small GTPase 2. | 0.995 |
NCF4 | NCF1 | ENSECAP00000036740 | ENSECAP00000012958 | Neutrophil cytosolic factor 4. | Neutrophil cytosolic factor 1. | 0.999 |
NCF4 | NCF2 | ENSECAP00000036740 | ENSECAP00000006755 | Neutrophil cytosolic factor 4. | Neutrophil cytosolic factor 2. | 0.999 |
NCF4 | PRKCA | ENSECAP00000036740 | ENSECAP00000036198 | Neutrophil cytosolic factor 4. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.411 |
NCF4 | PRKCB | ENSECAP00000036740 | ENSECAP00000042034 | Neutrophil cytosolic factor 4. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.952 |
NCF4 | PRKCD | ENSECAP00000036740 | ENSECAP00000021032 | Neutrophil cytosolic factor 4. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.944 |
NCF4 | RAC2 | ENSECAP00000036740 | ENSECAP00000036738 | Neutrophil cytosolic factor 4. | Rac family small GTPase 2. | 0.973 |
PLCG1 | PLCG2 | ENSECAP00000019222 | ENSECAP00000032104 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | Phosphoinositide phospholipase C. | 0.949 |