STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPHX2Epoxide hydrolase 2. (555 aa)    
Predicted Functional Partners:
CYP2J2
Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family.
  
 0.961
CYP2B6
Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family.
  
 0.941
LOC100061367
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.917
LOC100068569
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.917
LOC100070400
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.917
CYP2C113
Cytochrome P450 2C113; Belongs to the cytochrome P450 family.
  
 0.917
LOC100061400
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.917
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.871
LOC100065392
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.871
NUDT12
Nudix hydrolase 12.
  
 0.870
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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