STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (519 aa)    
Predicted Functional Partners:
HSPA8-2
Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family.
 
 0.854
HSPA8
Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]
 
 0.842
HSPA1A
Uncharacterized protein; Belongs to the heat shock protein 70 family.
 
 0.795
HSPA1L
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
 
 0.791
LOC111769297
Uncharacterized protein.
 
 0.787
HSPA2
Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.
 
 0.771
SGTA
Small glutamine rich tetratricopeptide repeat containing alpha.
   
 0.769
STIP1
Stress induced phosphoprotein 1.
   
 0.750
SGTB
Small glutamine rich tetratricopeptide repeat containing beta.
   
 0.746
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
 
 0.739
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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