STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL30Kelch like family member 30. (581 aa)    
Predicted Functional Partners:
PRPF40A
Pre-mRNA processing factor 40 homolog A.
    
 0.707
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
   
  
 0.697
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.662
WDR33
WD repeat domain 33.
    
 0.657
FBXO40
F-box protein 40.
   
  
 0.657
MARCHF7
Membrane associated ring-CH-type finger 7.
   
  
 0.654
UBE4A
Ubiquitination factor E4A.
     
 0.641
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.640
TRIM55
Tripartite motif containing 55.
   
 
 0.618
ASB8
Ankyrin repeat and SOCS box containing 8.
    
 0.587
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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