STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PENKProenkephalin. (266 aa)    
Predicted Functional Partners:
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.988
POMC
Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.
     
 0.977
OPRL1
Opioid related nociceptin receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.975
OPRK1
Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.973
PDYN
Prodynorphin.
    
0.952
SST
Somatostatin.
  
 
 0.825
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5.
      
 0.767
GAL
Galanin and GMAP prepropeptide.
     
 0.728
NPY
Neuropeptide Y.
   
 
 0.722
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.