STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HFM1Helicase for meiosis 1. (1480 aa)    
Predicted Functional Partners:
PRPF8
Pre-mRNA processing factor 8.
   
 0.875
PRPF6
Pre-mRNA processing factor 6.
   
 0.823
ASCC2
Activating signal cointegrator 1 complex subunit 2.
    
 0.821
WIPF3
WAS/WASL interacting protein family member 3.
    
 
 0.807
SLC35A3
Solute carrier family 35 member A3.
 
 
    0.786
FAM170B
Family with sequence similarity 170 member B.
    
 
 0.778
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
   
 0.775
ZNF644
Zinc finger protein 644.
   
 
 0.773
SNRPD3
Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
   
 0.768
EIF4ENIF1
Eukaryotic translation initiation factor 4E nuclear import factor 1.
   
 
 0.761
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.