STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N4BP1NEDD4 binding protein 1. (897 aa)    
Predicted Functional Partners:
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 
 0.870
RNF19B
RBR-type E3 ubiquitin transferase.
   
  
 0.773
RNF213
Ring finger protein 213.
      
 0.740
SLC35A2
Solute carrier family 35 member A2.
   
  
 0.695
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
   
  
 0.675
FAM117B
Family with sequence similarity 117 member B.
   
  
 0.659
NEDD4
NEDD4 E3 ubiquitin protein ligase.
   
 
 0.609
ZCCHC2
Zinc finger CCHC-type containing 2.
   
  
 0.588
FAM189B
Family with sequence similarity 189 member B.
   
  
 0.581
SEC62
SEC62 homolog, preprotein translocation factor.
   
  
 0.566
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.