CASTOR1 protein (Equus caballus) - STRING interaction network

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CASTOR1

Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa)

Predicted Functional Partners:

CASTOR2

0.995

MIOS

0.977

JMJD8

0.963

WDR59

0.963

SEC13

0.944

SLC38A9

0.758

ZC2HC1A

0.661

SESN1

0.652

NPRL3

0.651

BMT2

0.650

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	CASTOR1	ENSECAP00000019141	ENSECAP00000021775	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Cytosolic arginine sensor for mTORC1 subunit 1.	0.650
BMT2	CASTOR2	ENSECAP00000019141	ENSECAP00000016819	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.591
BMT2	JMJD8	ENSECAP00000019141	ENSECAP00000010654	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 24.	0.434
BMT2	MIOS	ENSECAP00000019141	ENSECAP00000019383	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Meiosis regulator for oocyte development.	0.423
BMT2	NPRL3	ENSECAP00000019141	ENSECAP00000044559	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR3 like, GATOR1 complex subunit.	0.815
BMT2	SESN1	ENSECAP00000019141	ENSECAP00000046769	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Sestrin 1.	0.458
BMT2	SLC38A9	ENSECAP00000019141	ENSECAP00000033997	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Solute carrier family 38 member 9.	0.489
BMT2	WDR59	ENSECAP00000019141	ENSECAP00000023616	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.433
CASTOR1	BMT2	ENSECAP00000021775	ENSECAP00000019141	Cytosolic arginine sensor for mTORC1 subunit 1.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.650
CASTOR1	CASTOR2	ENSECAP00000021775	ENSECAP00000016819	Cytosolic arginine sensor for mTORC1 subunit 1.	Uncharacterized protein.	0.995
CASTOR1	JMJD8	ENSECAP00000021775	ENSECAP00000010654	Cytosolic arginine sensor for mTORC1 subunit 1.	WD repeat domain 24.	0.963
CASTOR1	MIOS	ENSECAP00000021775	ENSECAP00000019383	Cytosolic arginine sensor for mTORC1 subunit 1.	Meiosis regulator for oocyte development.	0.977
CASTOR1	NPRL3	ENSECAP00000021775	ENSECAP00000044559	Cytosolic arginine sensor for mTORC1 subunit 1.	NPR3 like, GATOR1 complex subunit.	0.651
CASTOR1	SEC13	ENSECAP00000021775	ENSECAP00000042017	Cytosolic arginine sensor for mTORC1 subunit 1.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.944
CASTOR1	SESN1	ENSECAP00000021775	ENSECAP00000046769	Cytosolic arginine sensor for mTORC1 subunit 1.	Sestrin 1.	0.652
CASTOR1	SLC38A9	ENSECAP00000021775	ENSECAP00000033997	Cytosolic arginine sensor for mTORC1 subunit 1.	Solute carrier family 38 member 9.	0.758
CASTOR1	WDR59	ENSECAP00000021775	ENSECAP00000023616	Cytosolic arginine sensor for mTORC1 subunit 1.	WD repeat domain 59.	0.963
CASTOR1	ZC2HC1A	ENSECAP00000021775	ENSECAP00000029052	Cytosolic arginine sensor for mTORC1 subunit 1.	Zinc finger C2HC-type containing 1A.	0.661
CASTOR2	BMT2	ENSECAP00000016819	ENSECAP00000019141	Uncharacterized protein.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.591
CASTOR2	CASTOR1	ENSECAP00000016819	ENSECAP00000021775	Uncharacterized protein.	Cytosolic arginine sensor for mTORC1 subunit 1.	0.995