STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB11Serpin family B member 11 (gene/pseudogene); Belongs to the serpin family. (433 aa)    
Predicted Functional Partners:
TMPRSS11A
Transmembrane protease serine; Belongs to the peptidase S1 family.
   
 0.577
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.567
KLK12
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.525
KLK13
Kallikrein related peptidase 13; Belongs to the peptidase S1 family.
   
 0.518
TMPRSS13
Transmembrane serine protease 13; Belongs to the peptidase S1 family.
    
 0.517
TMPRSS4
Transmembrane serine protease 4; Belongs to the peptidase S1 family.
    
 0.515
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
   
 
 0.507
SPRR4
Small proline rich protein 4.
   
  
 0.490
IGSF9B
Immunoglobulin superfamily member 9B.
   
 
 0.485
GCSAML
Germinal center associated signaling and motility like.
      
 0.485
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.