STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMDHD1Amidohydrolase domain containing 1. (426 aa)    
Predicted Functional Partners:
FTCD
Formimidoyltransferase cyclodeaminase.
   
 
 0.990
UROC1
Urocanate hydratase 1.
  
 
 0.979
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 
 0.936
UPRT
Uracil phosphoribosyltransferase homolog.
  
 
 0.877
UPP1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
    
 0.831
NT5E
5'-nucleotidase ecto.
  
 
 0.802
PREX2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
   
  
 0.744
PTCHD4
Patched domain containing 4.
      
 0.651
TMEM178A
Transmembrane protein 178A.
      
 0.536
LOC100058685
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.523
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.