STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)    
Predicted Functional Partners:
HK2
Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis. Belongs to the hexokinase family.
   
 
 0.958
HK1
Hexokinase 1.
   
 
 0.958
HK3
Hexokinase 3.
   
 
 0.956
PGM1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
   
 
 0.955
HKDC1
Hexokinase domain containing 1.
   
 
 0.952
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 
 0.917
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
     
 0.917
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.907
G6PC
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
  
  
 
0.906
G6PC2
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
  
  
 
0.905
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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