STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)    
Predicted Functional Partners:
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
   
 0.999
PIK3R2
Uncharacterized protein.
   
 0.999
LOC100052122
Uncharacterized protein.
   
 0.997
CDC42
Cell division control protein 42-like protein.
   
 0.986
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
  
 
0.977
AKT2
Non-specific serine/threonine protein kinase.
   
 0.976
RAC1
Rac family small GTPase 1.
   
 0.970
MRAS
Muscle RAS oncogene homolog.
   
 0.966
EGFR
Receptor protein-tyrosine kinase.
    
 0.964
RAC2
Rac family small GTPase 2.
   
 0.964
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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