node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD48 | PROCR | ENSECAP00000011096 | ENSECAP00000021910 | CD48 molecule. | Protein C receptor. | 0.552 |
CHMP4B | PROCR | ENSECAP00000006395 | ENSECAP00000021910 | Charged multivesicular body protein 4B. | Protein C receptor. | 0.621 |
F2 | F2R | ENSECAP00000009701 | ENSECAP00000002827 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | 0.997 |
F2 | LOC100630489 | ENSECAP00000009701 | ENSECAP00000010335 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | C-X-C motif chemokine. | 0.469 |
F2 | PROC | ENSECAP00000009701 | ENSECAP00000026753 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.950 |
F2 | PROCR | ENSECAP00000009701 | ENSECAP00000021910 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Protein C receptor. | 0.721 |
F2 | TFPI | ENSECAP00000009701 | ENSECAP00000050197 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Tissue factor pathway inhibitor. | 0.708 |
F2 | THBD | ENSECAP00000009701 | ENSECAP00000003584 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Thrombomodulin. | 0.998 |
F2R | F2 | ENSECAP00000002827 | ENSECAP00000009701 | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.997 |
F2R | PROC | ENSECAP00000002827 | ENSECAP00000026753 | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.951 |
F2R | PROCR | ENSECAP00000002827 | ENSECAP00000021910 | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | Protein C receptor. | 0.738 |
F2R | THBD | ENSECAP00000002827 | ENSECAP00000003584 | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | Thrombomodulin. | 0.545 |
LOC100630489 | F2 | ENSECAP00000010335 | ENSECAP00000009701 | C-X-C motif chemokine. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.469 |
LOC100630489 | PROC | ENSECAP00000010335 | ENSECAP00000026753 | C-X-C motif chemokine. | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.588 |
LOC100630489 | PROCR | ENSECAP00000010335 | ENSECAP00000021910 | C-X-C motif chemokine. | Protein C receptor. | 0.558 |
PROC | F2 | ENSECAP00000026753 | ENSECAP00000009701 | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.950 |
PROC | F2R | ENSECAP00000026753 | ENSECAP00000002827 | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. | 0.951 |
PROC | LOC100630489 | ENSECAP00000026753 | ENSECAP00000010335 | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | C-X-C motif chemokine. | 0.588 |
PROC | PROCR | ENSECAP00000026753 | ENSECAP00000021910 | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | Protein C receptor. | 0.943 |
PROC | PROS1 | ENSECAP00000026753 | ENSECAP00000030358 | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | Protein S. | 0.648 |