STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYSMD3LysM domain containing 3. (306 aa)    
Predicted Functional Partners:
LYSMD2
LysM domain containing 2.
   
  
 0.900
ARRDC3
Arrestin domain containing 3.
   
  
 0.671
MFSD3
Major facilitator superfamily domain containing 3.
      
 0.631
APIP
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.
      
 0.483
CLK4
CDC like kinase 4; Belongs to the protein kinase superfamily.
   
  
 0.474
ADGRV1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.473
CTBS
Chitobiase; Belongs to the glycosyl hydrolase 18 family.
      
 0.471
PGLYRP4
Peptidoglycan recognition protein 4.
      
 0.470
CWC15
CWC15 spliceosome associated protein homolog.
   
  
 0.469
ACIN1
Apoptotic chromatin condensation inducer 1.
      
 0.461
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.