STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKLE2Ankyrin repeat and LEM domain containing 2. (942 aa)    
Predicted Functional Partners:
SIRT2
Sirtuin 2.
    
 0.914
BANF1
Barrier to autointegration factor 1.
    
 0.909
VRK2
VRK serine/threonine kinase 2.
   
 0.861
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
   
 0.861
ANKLE1
Ankyrin repeat and LEM domain containing 1.
   
 0.843
BANF2
Barrier to autointegration factor 2.
    
 0.804
EMD
Emerin.
   
 
 0.767
LEMD2
LEM domain containing 2.
   
 0.765
PPP2CB
Serine/threonine-protein phosphatase.
    
 0.701
TMEM203
Transmembrane protein 203.
      
 0.691
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.