STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLC1Modulator of VRAC current 1. (373 aa)    
Predicted Functional Partners:
KRCC1
Lysine rich coiled-coil 1.
      
 0.734
CDC14B
Uncharacterized protein.
      
 0.679
ACTRT1
Actin related protein T1; Belongs to the actin family.
   
  
 0.627
MPPE1
Metallophosphoesterase 1.
      
 0.553
TBXA2R
Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.547
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
      
 0.544
ATP1B1
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
 
 0.506
TRPV4
Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.485
TMEM106A
Transmembrane protein 106A.
      
 0.472
TMEM200A
Transmembrane protein 200A.
   
  
 0.443
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.