STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)    
Predicted Functional Partners:
GNAO1
G protein subunit alpha o1.
    
 0.973
HTR7
5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family.
    
  0.922
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
    
  0.918
CXCR4
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
   
  0.912
APLNR
Apelin receptor; Belongs to the G-protein coupled receptor 1 family.
   
  0.911
PREX1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
    
  0.906
KCNJ9
Potassium voltage-gated channel subfamily J member 9.
    
 0.904
LOC100050675
Uncharacterized protein.
     
  0.900
GNAL
G protein subunit alpha L.
   
 0.900
GNB2
G protein subunit beta 2.
   
 0.887
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]